Search results for "Gradient Pore Size"

An Innovative Method to Produce Scaffolds with a Pore Size Gradient for Tissue Engineering Applications

2014

Thermally Induced Phase Separation (TIPS) is a technique for the production of porous scaffold for Tissue Engineering applications. A wide range of microporous morphologies, in terms of pore size and distribution, can be obtained by tuning TIPS processing parameters, especially thermal history. The production of scaffolds for bone tissue regeneration is a challenging target: as a matter of fact, scaffolds must mimic the bone morphology, thus requiring a gradient of pore dimension and morphology along one dimension. To attain this goal, an experimental apparatus capable to impose different thermal histories on the two sides of a sample was designed, set up and tested. The sample (35x35 mm su…